| Primary Identifier | IPR029555 | Type | Family |
| Short Name | Serinc5 |
| description | Serine incorporator (Serinc) 1-5 constitute a family of carrier proteins that incorporate serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Serinc family members contain 11 transmembrane domains []. In the rat brain, expression of Serinc1 and Serinc2 mRNA is up-regulated by induced seizures, whereas Seric5 is down-regulated, indicating a novel mechanism linking neural activity and lipid biosynthesis.This entry represents Serinc5 (also known as Tpo1). It may play a role in myelin formation []. |
