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Protein Coding Gene : Clec1b C-type lectin domain family 1, member b

Primary Identifier  MGI:1913287 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  56760
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within platelet formation. Located in cell surface and plasma membrane. Is expressed in dorsal root ganglion; liver; lung; and spinal cord. Orthologous to human CLEC1B (C-type lectin domain family 1 member B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit congestion and hemorrhages during embryogenesis with prenatal and postnatal lethality. Mice homozygous for another knock-out allele exhibit blood-lymph mixing, impaired PDPN-Fc-mediated platelet activation, and intestinal edema. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1810061I13 gene,
  • Clec2,
  • expressed sequence AI465458,
  • MGI:2141425,
  • C-type lectin-like receptor 2,
  • C-type lectin domain family 1, member b,
  • Clec1b,
  • MGI:1923768,
  • Clec-2,
  • AI465458,
  • 1810061I13Rik

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

6 Pathways

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Expression

Gene --> Expression annotations

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Disease

Mouse features --> Human diseases

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