Primary Identifier | MGI:7561998 | Allele Type | Targeted |
Gene | Relb | Transmission | Germline |
Strain of Origin | C57BL/6NTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The targeting vector is designed to insert three point mutations (R117A / Y120A / E123A) in the 5' region of the gene. The mutations result in loss of κB-site specific DNA binding. The targeting construct also included an FRT-flanked neomycin (neo) cassette Flp-mediated recombination removed the neo cassette. |