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Protein Coding Gene : Slc41a3 solute carrier family 41, member 3

Primary Identifier  MGI:1918949 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  71699
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable magnesium:sodium antiporter activity. Predicted to be involved in mitochondrial magnesium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system; eye; hemolymphoid system; liver; and nervous system. Orthologous to human SLC41A3 (solute carrier family 41 member 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered magnesium ion homeostasis including hypomagnesemia. A subset of homozygotes develop severe unilateral hydronephrosis when fed a low magnesium diet. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI480742,
  • 1010001P06Rik,
  • RIKEN cDNA 1010001P06 gene,
  • Slc41a3,
  • solute carrier family 41, member 3,
  • SLC41A1-L2,
  • AI480742,
  • MGI:2141427

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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