Primary Identifier | MGI:5624990 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 105246908 |
Mgi Type | lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in several processes, including cardiac muscle hypertrophy in response to stress; epigenetic regulation of gene expression; and protein-RNA complex assembly. Part of ESC/E(Z) complex. Is active in nucleus. Orthologous to human CHAER1 (cardiac hypertrophy associated epigenetic regulator 1). PHENOTYPE: Knock-out of the gene reduces cardiac hypertrophy and fibrosis after surgically induced pressure overloading. [provided by MGI curators] |