|  Help  |  About  |  Contact Us

Allele : Aurka<tm1.2Sbsn> aurora kinase A; targeted mutation 1.2, Subrata Sen

Primary Identifier  MGI:5498678 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aurka
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. Cre-mediated recombination removed exon 2. Western blot analysis confirmed the absence of protein expression.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele