| Primary Identifier | MGI:97475 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 18484 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including metal ion binding activity; peptidylamidoglycolate lyase activity; and peptidylglycine monooxygenase activity. Predicted to be involved in several processes, including fatty acid primary amide biosynthetic process; peptide amidation; and response to zinc ion. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in several cellular components, including perikaryon; perinuclear region of cytoplasm; and trans-Golgi network. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; forelimb bud; limb interdigital region; and sensory organ. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase). PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality during fetal growth and development, edema, abnormal yolk sac vasculature, thin arterial walls, and abnormal bronchial epithelial morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
