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Protein Coding Gene : Mtnr1b melatonin receptor 1B

Primary Identifier  MGI:2181726 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  244701
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable melatonin receptor activity. Predicted to be involved in several processes, including negative regulation of cell communication; positive regulation of circadian sleep/wake cycle, non-REM sleep; and regulation of transmission of nerve impulse. Predicted to act upstream of or within circadian rhythm. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system; central nervous system; eye; and reproductive system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and display no obvious circadian phenotype. [provided by MGI curators]
  • synonyms:
  • melatonin receptor 1B,
  • Mel1b,
  • Mt2,
  • Mtnr1b

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For