| Primary Identifier | MGI:1194912 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 19646 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in DNA replication-dependent chromatin assembly; nucleosome assembly; and regulation of DNA-templated transcription. Predicted to act upstream of or within DNA replication and chromatin organization. Located in nucleus. Part of ESC/E(Z) complex and NuRD complex. Is expressed in several structures, including central nervous system; early conceptus; gonad; hemolymphoid system gland; and retina nuclear layer. Orthologous to human RBBP4 (RB binding protein 4, chromatin remodeling factor). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation. Cultured blastocysts fail to form typical outgrowth colonies. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
