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Allele : Scn4a<tm1.1Cann> sodium channel, voltage-gated, type IV, alpha; targeted mutation 1.1, Stephen C Cannon
Primary Identifier  MGI:5301528 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Scn4a
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 13 was replaced with an FRT-flanked neo cassette and a floxed exon 13 in which nucleotide substitutions (CGT to CAC) resulted in the amino acid substitution of histidine for arginine at position 669 (R669H). Two additional silent polymorphisms were inserted at codon 661 (GTG to GTA) and 662 (CTC to CTG). Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • R669H<m>,
  • SCN4A<R669H>,
  • R669H<m>,
  • SCN4A<R669H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele




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