| First Author | Kim YH | Year | 1993 |
| Journal | Gene | Volume | 133 |
| Issue | 2 | Pages | 267-71 |
| PubMed ID | 8224914 | Mgi Jnum | J:18669 |
| Mgi Id | MGI:66920 | Doi | 10.1016/0378-1119(93)90650-r |
| Citation | Kim YH, et al. (1993) Isolation and analysis of the rat genomic sequence encoding Cu/Zn superoxide dismutase. Gene 133(2):267-71 |
| abstractText | A rat genomic DNA (SOD1) encoding Cu/Zn superoxide dismutase (SOD1) (superoxide; superoxide oxidoreductase, EC 1.15.1.1) was cloned and sequenced. The rat SOD1 gene consisted of five exons and four introns spanning about 6 kb. The transcription start point (tsp) was observed 93 bp upstream from the ATG codon by primer extension analysis. The 5'-flanking sequence of SOD1 contained two CCAAT box motifs, a TATA box and four GC-like boxes. In the 3'-flanking region of SOD1, a polyadenylation signal, consensus sequence YGTGTTYY, and a G/T cluster were observed. A rat identifier (ID) sequence, a repetitive element of the rat genome, was located at between 569 and 484 bp upstream from the tsp. |
