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Publication : Effect of intra-rectal administration of boar seminal immunosuppressive fraction on mouse lymphocytes.

First Author  Veselský L Year  1994
Journal  J Reprod Fertil Volume  101
Issue  3 Pages  519-22
PubMed ID  7966005 Mgi Jnum  J:20431
Mgi Id  MGI:68520 Doi  10.1530/jrf.0.1010519
Citation  Veselsky L, et al. (1994) Effect of intra-rectal administration of boar seminal immunosuppressive fraction on mouse lymphocytes. J Reprod Fertil 101(3):519-22
abstractText  The repeated deposition of an immunosuppressive fraction isolated from boar vesicular gland secretion into the rectum of healthy male and female mice reduced responses of lymphocytes to mitogens in vitro. Rectal deposition of the immunosuppressive component also led to a decrease in the activity of plaque-forming cells. These findings indicate that repeated rectal deposition of semen may compromise some aspects of the immune system and may be an important cofactor in the development of viral or bacterial infections among homosexual men.
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