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Publication : Expression of Epiplakin1 in the developing and adult mouse retina.

First Author  Yoshida T Year  2010
Journal  Jpn J Ophthalmol Volume  54
Issue  1 Pages  85-8
PubMed ID  20151282 Mgi Jnum  J:160850
Mgi Id  MGI:4455254 Doi  10.1007/s10384-009-0751-y
Citation  Yoshida T, et al. (2010) Expression of Epiplakin1 in the developing and adult mouse retina. Jpn J Ophthalmol 54(1):85-8
abstractText  PURPOSE: To assess the expression of Epiplakin1 (Eppk1) in the developing and adult mouse retina. METHODS: Eppk1 expression was examined using reverse transcription-polymerase chain reaction (RTPCR) analysis and immunoblot analysis. The Eppk1 expression pattern was examined by immunohistochemical analysis in embryonic and adult C57BL/6J mice. RESULTS: Both Eppk1 mRNA and protein were detected in adult mouse retina. Eppk1 was expressed in nestin-positive neural progenitor cells in the embryonic retina. In adults, Eppk1 was expressed in retinal ganglion cells, bipolar cells, and Muller glial cells. CONCLUSIONS: These results suggest that Eppk1 is expressed both in embryonic and adult retina and may be involved in retinal development.
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