First Author | Yoshida T | Year | 2010 |
Journal | Jpn J Ophthalmol | Volume | 54 |
Issue | 1 | Pages | 85-8 |
PubMed ID | 20151282 | Mgi Jnum | J:160850 |
Mgi Id | MGI:4455254 | Doi | 10.1007/s10384-009-0751-y |
Citation | Yoshida T, et al. (2010) Expression of Epiplakin1 in the developing and adult mouse retina. Jpn J Ophthalmol 54(1):85-8 |
abstractText | PURPOSE: To assess the expression of Epiplakin1 (Eppk1) in the developing and adult mouse retina. METHODS: Eppk1 expression was examined using reverse transcription-polymerase chain reaction (RTPCR) analysis and immunoblot analysis. The Eppk1 expression pattern was examined by immunohistochemical analysis in embryonic and adult C57BL/6J mice. RESULTS: Both Eppk1 mRNA and protein were detected in adult mouse retina. Eppk1 was expressed in nestin-positive neural progenitor cells in the embryonic retina. In adults, Eppk1 was expressed in retinal ganglion cells, bipolar cells, and Muller glial cells. CONCLUSIONS: These results suggest that Eppk1 is expressed both in embryonic and adult retina and may be involved in retinal development. |