First Author | Long B | Year | 2015 |
Journal | Sci Rep | Volume | 5 |
Pages | 18426 | PubMed ID | 26689553 |
Mgi Jnum | J:244837 | Mgi Id | MGI:5913616 |
Doi | 10.1038/srep18426 | Citation | Long B, et al. (2015) 3D Image-Guided Automatic Pipette Positioning for Single Cell Experiments in vivo. Sci Rep 5:18426 |
abstractText | We report a method to facilitate single cell, image-guided experiments including in vivo electrophysiology and electroporation. Our method combines 3D image data acquisition, visualization and on-line image analysis with precise control of physical probes such as electrophysiology microelectrodes in brain tissue in vivo. Adaptive pipette positioning provides a platform for future advances in automated, single cell in vivo experiments. |