Type | MGI:General | Description | pretreatment of macrophages with IFNG fails to reduce the number of L. major amastigotes within the macrophage unlike in wild-type cells uninfected cells produce more nitrite both basally and in response to IFNG stimulation compared to wild-type cells; however, infected cells stimulated with IFNG produce less nitrite compared to infected wild-type cells decrease in IFNG stimulated TNF production and L. major infection fails to induce TNF production in macrophages |