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Allele : Bmpr1a<tm2.2Bhr> bone morphogenetic protein receptor, type 1A; targeted mutation 2.2, Richard R Behringer

Primary Identifier  MGI:2181295 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bmpr1a
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination introduced a floxed neomycin resistance cassette into intron 2, and a single loxP site into intron 1. Cre-mediated recombination in vivo under the control of a CMV promoter excised the neo cassette and exon 2, which encodes roughly a third of the extracellular domain of the receptor within the ligand-binding domain.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Bmpr1a<->,
  • deltaexon2,
  • deltaexon2,
  • deltae2,
  • Bmpr1a<->,
  • deltae2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele