First Author | Nomura M | Year | 1994 |
Journal | FEBS Lett | Volume | 348 |
Issue | 2 | Pages | 201-5 |
PubMed ID | 8034042 | Mgi Jnum | J:19200 |
Mgi Id | MGI:67394 | Doi | 10.1016/0014-5793(94)00608-3 |
Citation | Nomura M, et al. (1994) One of the retinoic acid-inducible cDNA clones in mouse embryonal carcinoma F9 cells encodes a novel isoenzyme of fructose 1,6-bisphosphatase. FEBS Lett 348(2):201-5 |
abstractText | Rae-30, one of the retinoic acid (RA)-inducible cDNA clones in mouse embryonal carcinoma F9 cells, was sequenced and the deduced RAE-30 protein showed about a 70% homology to mammalian fructose 1,6-bisphosphatase (EC 3.1.3.11) (FBPase), in comparison to over 85% homology observed among the previously documented rat liver, pig kidney and human leukemic HL-60 cell FBPases. The Rae-30 mRNAs were not detected in various tissues of adult mice, including the liver and kidney, but were detected in a placenta and predominantly in the intestine of adult mice. These findings indicate that the Rae-30 cDNA encodes a novel isoenzyme of FBPase, which is likely to be involved in early differentiation in mammalian cells. |