| First Author | Damjanov I | Year | 1994 |
| Journal | Biochem Biophys Res Commun | Volume | 201 |
| Issue | 2 | Pages | 994-1000 |
| PubMed ID | 8003041 | Mgi Jnum | J:18661 |
| Mgi Id | MGI:66917 | Doi | 10.1006/bbrc.1994.1800 |
| Citation | Damjanov I, et al. (1994) Molecular cloning and characterization of murine cyclin E. Biochem Biophys Res Commun 201(2):994-1000 |
| abstractText | Using a monoclonal antibody developed to a mouse trophectodermal carcinoma stem cell line E6496D lysate, we have identified the gene that encodes murine cyclin E. The cDNA contains a consensus cyclin box and a long 3' untranslated region and shares over 75% homology with human cyclin E cDNA. We show that the gene is expressed in fetal tissues, embryonal carcinoma F9 cells and yolk sac carcinoma PYS-2 cells, but is not expressed in preimplantation stages of development. In adult tissues, cycE mRNA is detectable in the spleen and to a lesser extent in the testis and brain. These data show that cycE is developmentally regulated and unevenly expressed in fetal and adult mouse tissues. |
