Primary Identifier | MGI:2442191 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 319520 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable phosphoprotein phosphatase activity. Predicted to be involved in endoderm formation and negative regulation of ERK1 and ERK2 cascade. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in nervous system; olfactory epithelium; and unsegmented mesenchyme. Orthologous to human DUSP4 (dual specificity phosphatase 4). PHENOTYPE: Mice homozygous for a null allele exhibit a decrease in B cell apoptosis of bone marrow-derived, IL-7-dependent pro-B lymphocytes. [provided by MGI curators] |