| Primary Identifier | MGI:1924937 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226922 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables voltage-gated potassium channel activity. Acts upstream of or within potassium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of clathrin coat and voltage-gated potassium channel complex. Predicted to be active in calyx of Held and presynaptic membrane. Is expressed in heart. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 46. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5). PHENOTYPE: Mice homozygous for a dominant negative knock-in mutation in this gene exhibit partial prenatal lethality and abnormal afterhyperpolarization in the in the CA3 area of hippocampus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
