Primary Identifier | MGI:1919290 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72040 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable beta-catenin binding activity; calcium ion binding activity; and cell adhesion molecule binding activity. Predicted to be involved in intermicrovillar adhesion and regulation of microvillus length. Predicted to act upstream of or within cell differentiation. Predicted to be located in apical plasma membrane; cell projection membrane; and clathrin-coated pit. Is expressed in liver; lung; metanephros; placenta; and yolk sac. Orthologous to human CDHR5 (cadherin related family member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a slight increase of cell proliferation in the intestinal epithelium but no significant alterations in lifespan or spontaneous tumor incidence. [provided by MGI curators] |