Primary Identifier | MGI:96836 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 16993 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ether hydrolase activity; metalloaminopeptidase activity; and zinc ion binding activity. Predicted to be involved in leukotriene biosynthetic process; peptide catabolic process; and protein metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human LTA4H (leukotriene A4 hydrolase). PHENOTYPE: Mice homozygous for disruptions in this gene have grossly normal phenotypes. Inflammatory reactions are reduced as are some other immunological responses. [provided by MGI curators] |