| First Author | Gervasi F | Year | 1998 |
| Journal | DNA Cell Biol | Volume | 17 |
| Issue | 12 | Pages | 1047-55 |
| PubMed ID | 9881672 | Mgi Jnum | J:51849 |
| Mgi Id | MGI:1327035 | Doi | 10.1089/dna.1998.17.1047 |
| Citation | Gervasi F, et al. (1998) Identification of novel mRNA transcripts of the nm23-M1 gene that are modulated during mouse embryo development and are differently expressed in adult murine tissues. DNA Cell Biol 17(12):1047-55 |
| abstractText | The nm23-M1, a putative metastasis-suppressor gene, and its homologs are involved in development and differentiation. We have shown previously that in vitro neuronal cell proliferation and differentiation can be modulated by nm23-M1 expression levels. In the present study, by the yeast two-hybrid system, we have shown that, at the onset of mouse tissue differentiation, the Nm23-M1 protein forms either homodimers, or heterodimers with Nm23-M2. Furthermore, we have isolated two cDNA variants of the nm23-M1 gene in the 3'-untranslated region (UTR). The two variants related to novel mRNA transcripts that are modulated in mouse embryo and are differently expressed in adult murine tissues. |
