First Author | Li L | Year | 2002 |
Journal | Clin Immunol | Volume | 102 |
Issue | 2 | Pages | 135-7 |
PubMed ID | 11846454 | Mgi Jnum | J:75147 |
Mgi Id | MGI:2175996 | Doi | 10.1006/clim.2001.5155 |
Citation | Li L, et al. (2002) Prevention of murine experimental autoimmune orchitis by recombinant human interleukin-6. Clin Immunol 102(2):135-7 |
abstractText | We studied the effect of exogenously administered recombinant human interleukin (IL)-6 on the development of experimental autoimmune orchitis (EAO) in C3H/Hej mice. IL-6 significantly reduced histological signs of EAO and appearance of delayed type hypersensitivity against the immunizing testicular germinal cells. The effect was seen even though the cytokine was administered for only 6 consecutive days and 2 weeks after immunization. |