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Publication : Prevention of murine experimental autoimmune orchitis by recombinant human interleukin-6.

First Author  Li L Year  2002
Journal  Clin Immunol Volume  102
Issue  2 Pages  135-7
PubMed ID  11846454 Mgi Jnum  J:75147
Mgi Id  MGI:2175996 Doi  10.1006/clim.2001.5155
Citation  Li L, et al. (2002) Prevention of murine experimental autoimmune orchitis by recombinant human interleukin-6. Clin Immunol 102(2):135-7
abstractText  We studied the effect of exogenously administered recombinant human interleukin (IL)-6 on the development of experimental autoimmune orchitis (EAO) in C3H/Hej mice. IL-6 significantly reduced histological signs of EAO and appearance of delayed type hypersensitivity against the immunizing testicular germinal cells. The effect was seen even though the cytokine was administered for only 6 consecutive days and 2 weeks after immunization.
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