Primary Identifier | IPR028769 | Type | Family |
Short Name | LEF1 |
description | Lymphoid enhancer-binding factor 1 (LEF-1) belongs to the LEF-1/TCFs (T cell factors) family of transcription factors []. LEF-1 participates in the Wnt signalling pathway, performing its function in complexes with beta-catenin [, , ]. LEF-1 may also acquire diverse regulatory functions by association with Wnt/beta-catenin-independent stimuli, such as the TGF-beta and Notch pathways [, ]. |