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Protein Domain : TATA box-binding protein-associated factor RNA polymerase I subunit A

Primary Identifier  IPR039495 Type  Family
Short Name  TAF1A
description  TATA box binding protein associated factor RNA Polymerase I subunit A (TAF1A/TAFI48) is found in eukaryotes and is encoded by the gene TAF1A in humans. Its function is to aid transcription of DNA into RNA by binding to the promoter at the -10 TATA box site. It is a component of the transcription factor SL1/TIF-IB complex, involved in PIC assembly (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation depends on the rate of association of this protein. This protein also stabilises nucleolar transcription factor 1/UBTF on rDNA [, ].This entry also includes TAF1A homologues from plants.

1 Child Features

0 Parent Features

4 Protein Domain Regions