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Allele : Pcdhg<em25Rwb> protocadherin gamma cluster; endonuclease-mediated mutation 25, Robert W Burgess
Primary Identifier  MGI:6285811 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Pcdhg
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was generated through shotgun CRISPR/Cas9 editing using pooled sgRNAs that targeted each variable exon of the Pcdhg cluster and this allele was found to have frame shifting indels in variable exons A2, A3, and A10 and a structural rearrangement impacting exons A11, B8, and A12.
  • mutations:
  • Intragenic deletion
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