| First Author | Drinkwater CC | Year | 1988 |
| Journal | J Biol Chem | Volume | 263 |
| Issue | 18 | Pages | 8565-8 |
| PubMed ID | 3288617 | Mgi Jnum | J:9214 |
| Mgi Id | MGI:57677 | Doi | 10.1016/s0021-9258(18)68341-3 |
| Citation | Drinkwater CC, et al. (1988) Sequence and expression of mouse gamma-renin. J Biol Chem 263(18):8565-8 |
| abstractText | Mouse gamma-renin is a member of the group of serine proteases known as glandular kallikreins. These highly homologous proteins process a diverse range of growth factors and hormones to their biologically active form, usually by cleavage at a basic residue. gamma-Renin, however, cleaves at a Leu-Leu bond in a similar fashion to renin. We have identified and sequenced the gene and a cDNA encoding gamma-renin. The complete predicted amino acid sequence was determined, and residues that may be important in the unusual cleavage pattern exhibited by gamma-renin are discussed. The nucleotide sequence enabled design of a gene-specific oligodeoxyribonucleotide which was used to determine in which mouse tissues gamma-renin is expressed. |
