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Publication : High-resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in ffttle standard karyotypes.

First Author  Iannuzzi L Year  1996
Journal  Cytogenet Cell Genet Volume  75
Issue  1 Pages  10-3
PubMed ID  8995479 Mgi Jnum  J:37355
Mgi Id  MGI:84756 Doi  10.1159/000134446
Citation  Iannuzzi L, et al. (1996) High-resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in ffttle standard karyotypes. Cytogenet Cell Genet 75(1):10-3
abstractText  High-resolution chromosomal fluorescence in situ hybridization (FISH) and R-banding allowed the chromosomal localization of the beta-defensin gene cluster (DEFB@) to chromosome band 1p12 in the river buffalo (Bubalus bubalis, 2n = 50) and to band 24q13 in sheep (Ovis aries, 2n = 54), according to standard nomenclatures. The localizations permitted the tentative assignment of the entire bovine syntenic group U25 to these chromosomes. A FISH mapping control on cattle chromosomes confirmed the localization of DEFB@ in the homoeologous chromosome and chromosome band. Comparisons were made between river buffalo chromosome 1p and the homoeologous cattle chromosome on standard karyotypes; the results are discussed in light of gene assignments, extensive chromosome band conservation among the Bovidae, and inconsistencies in domestic cattle chromosome nomenclatures.
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