| Type | MGI:General | Description | whole-cell recordings from hypoglossal motoneurons at a holding potential of -70 mV indicate that during periods without obvious IPSCs, the average noise values recorded from mutant neurons are significantly higher than those observed in wild-type cells the average interval of IPSCs identified in mutant hypoglossal motoneurons is significantly lower than in wild-type cells, whereas the average IPSC amplitude is not significantly smaller than that in wild-type cells the IPSC decay time is significantly longer in mutant neurons relative to wild-type cells application of strychnine decreases the steady-state holding current in mutant hypoglossal motoneurons and reduces synaptic noise to wild-type levels |
