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Protein Coding Gene : Mdk midkine

Primary Identifier  MGI:96949 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  17242
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chondroitin sulfate binding activity and heparin binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cell adhesion; and positive regulation of leukocyte migration. Predicted to be located in cell projection. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in brain ischemia. Orthologous to human MDK (midkine).
PHENOTYPE: Mice homozygous for disruptions in this gene are essentially normal except for some delayed development of the hippocampus and behavioral abnormalities when young. [provided by MGI curators]
  • synonyms:
  • midkine,
  • midgestation embryo & kidney gene,
  • MGD-MRK-12166,
  • MK,
  • Mdk,
  • Mek,
  • MGD-MRK-12189

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For