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Protein Coding Gene : Gbp4 guanylate binding protein 4
Primary Identifier  MGI:97072 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  17472
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ubiquitin-protein transferase inhibitor activity. Involved in negative regulation of interferon-alpha production. Acts upstream of or within several processes, including cellular response to type II interferon; negative regulation of macromolecule metabolic process; and negative regulation of protein import into nucleus. Predicted to be located in Golgi apparatus; membrane; and nucleus. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP6 (guanylate binding protein family member 6).
  • synonyms:
  • MGD-MRK-12401,
  • Gbp4,
  • MGD-MRK-12403,
  • macrophage activation 2,
  • guanylate binding protein 4,
  • expressed sequence AW228052,
  • Mpa2,
  • AW228052,
  • Mag-2,
  • Mpa-2,
  • MGI:2141182
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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