| Type | MGI:General | Description | cultured medium spiny neurons are resistant to NMDAR-mediated excitotoxicity compared to wild-type (2.4% apoptotic cells vs 8.6% in wild-type cultures) in vivo, quinolinic acid-induced lesion volume is less than that observed in wild-type mice medium spiny neurons exposed to staurosporine show less cell death than wild-type neurons in culture (20% apoptotic cells vs 36.8% in wild-type cultures) |
