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Protein Domain : Forkhead box protein J2/3-like

Primary Identifier  IPR045912 Type  Family
Short Name  FOXJ2/3-like
description  This entry represents a group of fork-head domain-containing proteins, including the transcriptional activators FOXJ2/3 from humans.In humans FOXJ2 has two isoforms, FHX.L and FHX.S. FHX. L can bind to two different type of DNA binding sites. The levels of FOXJ2 expression have been linked to a variety of cancers [, , , , ]. The expression of FOXJ3 is associated with cancers and rheumatoid arthritis [, ].In mice FOXJ2 is involved in the regulation of meiosis during spermatogenesis [].

0 Child Features

0 Parent Features

9 Protein Domain Regions