| First Author | Matsuo N | Year | 1998 |
| Journal | Gene | Volume | 215 |
| Issue | 2 | Pages | 477-81 |
| PubMed ID | 9714847 | Mgi Jnum | J:49545 |
| Mgi Id | MGI:1277682 | Doi | 10.1016/s0378-1119(98)00324-2 |
| Citation | Matsuo N, et al. (1998) A novel SCG10-related gene uniquely expressed in the nervous system. Gene 215(2):477-81 |
| abstractText | We have isolated a novel cDNA (HiAT3: hippocampus abundant transcript 3) in the course of screening for genes that are preferentially expressed in neonatal mouse hippocampus using random 3'-directed cDNA sequencing approach. It encodes a 180-aa protein that has high similarity to SCG10, a neuron-specific negative regulator of microtubule dynamics during neurite outgrowth. The expression of HiAT3 is limited to neurons and peaks about 1 week after birth. The identification of HiAT3 suggests that there may be an elaborate destabilizing regulation for microtubule dynamics in neurons in addition to the stabilizing effect of multiple microtubule-associated proteins (MAPs). |
