| First Author | Staeheli P | Year | 1988 |
| Journal | Mol Cell Biol | Volume | 8 |
| Issue | 10 | Pages | 4524-8 |
| PubMed ID | 2460745 | Mgi Jnum | J:9453 |
| Mgi Id | MGI:57913 | Doi | 10.1128/mcb.8.10.4524 |
| Citation | Staeheli P, et al. (1988) Identification of a second interferon-regulated murine Mx gene. Mol Cell Biol 8(10):4524-8 |
| abstractText | The murine influenza virus resistance locus Mx consists of more than one interferon-responsive transcription unit. We isolated clones of the transcripts of a second Mx gene (Mx2) which is closely linked to the well-characterized resistance gene and determined their sequences. Mx2 mRNA is more than 90% identical to Mx1 mRNA in the region corresponding to the amino termini of the encoded proteins. Mx2 mRNAs of mouse strains BALB/c and CBA have open reading frames apparently interrupted by mutations. Interferon-treated cells from strain A2G and other influenza virus-resistant strains failed to express detectable amounts of Mx2 transcripts. |
