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Comment :

Type  MGI:General Description  at day 15 after s.c. injection of B16F10 melanoma cells, the number of CD31-positive microvessels within tumor tissue is lower than that in wild-type controls, indicating impaired tumor angiogenesis at day 18 after s.c. injection of B16F10 cells, the number of mature (both CD31-positive and smooth muscle actin (SMA)-positive) microvessels is significantly lower than that observed at day 15 in wild-type controls impaired tumor angiogenesis and microvessel maturation is also noted following s.c. injection of Lewis Lung carcinoma (LLC) cells or fat pad injection of E0771 breast cancer cells