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Allele : Del(2Hoxd12-Hoxd13)6Ddu deletion, Chr 2, Denis Duboule 6
Primary Identifier  MGI:2445999 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(2Hoxd12-Hoxd13)6Ddu
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Hoxd13, Hoxd 12, and regions X, XI, and XII were deleted via trans-allelic meiotic recombination (TAMERE). The deletion was accomplished by recombination of a single loxP site in the intergenic region between Evx2 and Hoxd13 that had replaced region XII (Evx2/Hoxd13tm3.1Ddu) and a single loxP on the opposite chromosome 303 bp upstream of a 261 bp deletion of region X (Hoxdtm4.1Ddu).
  • mutations:
  • Intragenic deletion,
  • Intergenic deletion
  • synonyms:
  • HoxD<RXII-del(13-12)>,
  • Hoxd<tm9Ddu>,
  • Hoxd<tm9Ddu>,
  • Del6Ddu,
  • Del6Ddu,
  • HoxD<RXII-del(13-12)>
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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