| Primary Identifier | IPR032921 | Type | Family |
| Short Name | PRC1 |
| description | PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone []. It is a key regulator of cytokinesis that cross-links antiparallel microtubules at an average distance of 35 nM [, ]. PRC1 is also required for KIF14 (a kinesin-3 family motor protein) localisation to the central spindle and midbody [, , ]and is required to recruit PLK1 to the spindle. It stimulates PLK1 phosphorylation of RACGAP1/HsCyk-4 to allow recruitment of ECT2 to the central spindle []. |
