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Protein Domain : Tyrosine-protein kinase TXK, SH3 domain

Primary Identifier  IPR035579 Type  Domain
Short Name  TXK_SH3
description  TXK is a member of the Tec family, which is a group of nonreceptor tyrosine kinases containing Src homology protein interaction domains (SH3, SH2) N-terminal to the catalytic tyr kinase domain. It also contains an N-terminal cysteine-rich region. TXK forms a complex with EF-1alpha and PARP1 that regulates interferon-gamma gene transcription in Th1 cells []. This entry represents the SH3 domain of TXK.

0 Child Features

1 Parent Features

3 Protein Domain Regions