| Primary Identifier | MGI:1321119 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20871 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables protein kinase activity. Predicted to be involved in mitotic spindle organization and regulation of cytokinesis. Predicted to act upstream of or within cell division; meiotic cell cycle; and phosphorylation. Located in chromosome, centromeric region and meiotic spindle midzone. Is expressed in brain; gonad; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKC (aurora kinase C). PHENOTYPE: Male mice homozygous for a knock-out allele are viable but subfertile, as shown by reduced litter sizes or failure to produce a litter. Observed sperm abnormalities include heterogeneous chromatin condensation, loose acrosomes, and blunted heads. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
