Primary Identifier | MGI:2388044 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dgke |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1 of the gene was replaced with a neomycin resistance cassette via homologous recombination. The targeted mutation results in deletion of the translation initiation codon, the entire first C1 domain, and most of the second C1 domain. |