First Author | Richards S | Year | 1989 |
Journal | EMBO J | Volume | 8 |
Issue | 12 | Pages | 3749-57 |
PubMed ID | 2573520 | Mgi Jnum | J:10105 |
Mgi Id | MGI:58562 | Doi | 10.1002/j.1460-2075.1989.tb08551.x |
Citation | Richards S, et al. (1989) Genetic and molecular mapping of the Hmt region of mouse. EMBO J 8(12):3749-57 |
abstractText | We have mapped a new region of the mouse major histocompatibility complex (MHC) that contains the nuclear gene, Hmt, for the maternally transmitted antigen, Mta. The Hmt region of chromosome 17 lies between a recombinational breakpoint distal to Tla and another proximal to Tpx-1, thus including Pgk-2. A novel MHC class I gene fragment, R4B2, was cloned and mapped to this region as was another new class I gene, Thy19.4. Both lie proximal to Pgk-2, within the distal inversion in t-haplotypes. The presence of several other MHC class I genes in the Hmt region is predicted from analysis of the recombinants that define the region. |