| Primary Identifier | MGI:98488 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21366 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables beta-alanine transmembrane transporter activity; gamma-aminobutyric acid:sodium:chloride symporter activity; and taurine:sodium symporter activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within beta-alanine transport and taurine transmembrane transport. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in several structures, including brain; cardiovascular system; retina; spinal cord mantle layer; and tooth. Used to study retinitis pigmentosa. Orthologous to human SLC6A6 (solute carrier family 6 member 6). PHENOTYPE: Homozygous mutant mice have impaired vision associated with retinal degeneration. In addition to the visual defects, mutant mice exhibit reduced female fertility and decreased levels of taurine in a variety of tissues. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
