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Protein Coding Gene : Wipf3 WAS/WASL interacting protein family, member 3
Primary Identifier  MGI:3044681 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  330319
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable SH3 domain binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within cell differentiation and spermatogenesis. Is active in synapse. Orthologous to human WIPF3 (WAS/WASL interacting protein family member 3).
PHENOTYPE: Mice homozygous for a knock-out allele display impaired spermatogenesis, abnormal sperm head morphology, and significantly reduced male fertility. Female fertility is not affected. [provided by MGI curators]
  • synonyms:
  • Wipf3,
  • expressed sequence AV348454,
  • BQ952480,
  • WAS/WASL interacting protein family, member 3,
  • expressed sequence BQ952480,
  • MGI:2141631,
  • AV348454
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Trail: ProteinCodingGene

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