| Primary Identifier | MGI:2140940 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 100705 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables acetyl-CoA carboxylase activity. Involved in several processes, including malonyl-CoA biosynthetic process; negative regulation of fatty acid beta-oxidation; and positive regulation of heart growth. Acts upstream of or within fatty acid biosynthetic process. Located in mitochondrion. Is expressed in axial skeleton; cranium; and liver. Orthologous to human ACACB (acetyl-CoA carboxylase beta). PHENOTYPE: Mice homozygous for a targeted null mutation are viable, fertile and overtly normal but exhibit high levels of fatty acid oxidation, as well as reduced fat accumulation in their adipose tissue and liver, and decreased storage of glycogen in their liver. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
