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Allele : Grap<tm1Gsf> GRB2-related adaptor protein; targeted mutation 1, Gen-Sheng Feng

Primary Identifier  MGI:2179974 Allele Type  Targeted
Attribute String  Null/knockout Gene  Grap
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An exon encoding amino acids 160-217 was replaced with a neomycin resistance cassette via homologous recombination. Southern blot analysis confirmed the targeted allele. Western blot of lymphocytes from homozygous mutant animals could not determine conclusively if the protein was absent or merely truncated.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Grap-,
  • Grap-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele