Primary Identifier | MGI:2180770 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd48 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced the exon encoding the immunoglobulin-V-like domain, which forms a binding site for the Cd2 antigen. Thymocytes and splenocytes isolated from homozygous mutant mice were found to lack surface expression of the endogenous protien. |