| First Author | Paris A | Year | 1995 |
| Journal | FEBS Lett | Volume | 369 |
| Issue | 2-3 | Pages | 326-30 |
| PubMed ID | 7649281 | Mgi Jnum | J:47503 |
| Mgi Id | MGI:1203650 | Doi | 10.1016/0014-5793(95)00777-7 |
| Citation | Paris A, et al. (1995) Molecular cloning and sequence analysis of human preprocathepsin C. FEBS Lett 369(2-3):326-30 |
| abstractText | A cDNA clone (C1) coding for human preprocathepsin C was isolated from a human ileum cDNA library using a rat kidney-derived RT-PCR probe and its complete nucleotide sequence determined. The full-length 1857 bp sequence codes for a protein of 463 amino acid residues with a calculated molecular mass of 51848 Da. Comparison of the deduced amino acid sequence with that of rat preprocathepsin C indicates an 87.5% identity. A multiple alignment of the deduced cathepsin C sequence of 233 residues which, by analogy to other cystein proteinases, corresponds to the mature protein, confirms that human cathepsin C belongs to the papain superfamily. |
