Primary Identifier | MGI:5142240 | Allele Type | Targeted |
Attribute String | Reporter | Gene | Fos |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4 was replaced with a modified exon in which nucleotide substitutions result in the amino acid substitution of alanine for serine at positions 362 and 374 (S362A and S374A). Flp-mediated recombination removed the floxed neo cassette inserted downstream of the endogenous polyadenylation sequence and left an EGFP gene with a 5' loxP site intact. |